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Moghimi N, Eslami Farsani B, Ghadipasha M, et al
GLP-1s and Metabolic Health Metabolic dysfunction, which includes conditions like obesity, type 2 diabetes, and metabolic syndrome, is often at the core of many chronic diseases
Cancer metabolism is a factor that might be exploited as a potential therapeutic target for drug discovery also on how a cancer cell differs in its metabolism to that of a rapidly proliferating normal cell (Vander Heiden et al
The mechanism of action includes several key effects: Enhancing insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps lower blood sugar levels Suppressing glucagon release , thereby reducing glucose production by the liver Slowing gastric emptying , which prolongs the feeling of fullness after meals Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger and food intake Most GLP-1 medications are administered via subcutaneous injection , either once weekly (semaglutide, dulaglutide) or once daily (liraglutide), depending on the specific formulation
