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Patients carrying the GLP1R rs6923761 variant may experience faster appetite suppression onset, meaning a morning injection could trigger stronger nausea during peak workday hours, while evening timing might suit their biology better

Faster rates, while sometimes achievable short term, rarely sustain long term and may indicate excessive caloric restriction that will trigger metabolic adaptation

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This reaction is usually temporary and can often be mitigated by staying well-hydrated and taking the peptide with food

Poster presented at ISPOR 2024, Inovalon, Bowie, MD, United States.

Other possible side effects include injection site redness, itching, swelling, pain, skin thickening, skin pits, weight gain, and fluid retention