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The magnitude of this effect varies with GH pulse amplitude and duration again favoring robust pulsatile protocols (CJC-1295/ipamorelin) over gentle stimulation (sermorelin alone)

What specific tissues show the greatest response to ipamorelin in animal models? Bone (trabecular and cortical), skin (dermal collagen), tendon/ligament connective tissue, and skeletal muscle show the most consistent responses in published studies

Bob et al., 2019), pre-dialysis versus dialysis (Liu et al., 2019a

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