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Oligodendrocytes are notably susceptible to hypoxia [278], and the oxidative stress resulting from chronic hypoxia is a critical mechanism in neurodegeneration and axonal loss in multiple sclerosis

But it would be wise to take a daily multi-vitamin that contains the critical cofactors Vitamin C, E, B1, B2, B3, B9, B12, Selenium, Magnesium, and Zinc

Bioisosteric modification on melatonin: synthesis of new naphthalene derivatives, in vitro antioxidant activity and cytotoxicity studies

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479 A preclinical study indicated that, 480 adjunctive treatment with SG1002 can enhance circulating and tissue levels of H 2 S, alleviating cardiac dysfunction in HFpEF and significantly reducing cardiac interstitial fibrosis