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however, resistance remains a significant issue (26)

a posttranslationally modified bacteriocin with a narrow spectrum of activity against Clostridium difficile

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Interestingly, silencing of oct 3 transporter in mice attenuates both the MPP + release from astrocytes and the subsequent impairment of dopaminergic neurons, in which makes oct3 as an important molecular target for dopaminergic related pathologies [6,84]

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