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However, individuals with absorption disorders may require significantly higher doses to achieve therapeutic levels

Nonetheless, this work has identified novel findings that support future studies to determine whether microbiome changes are contingent upon the combination of both NNMTi and LD switch and mediated through direct NNMTi-driven mechanisms or through indirect mechanisms such as weight or fat loss 8,13

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(2003) Journal of Clinical Endocrinology & Metabolism n=120 Phase 2 double-blind trial of AOD 9604 5mg daily versus placebo in obese subjects measuring weight loss and lipid changes

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