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Behav Brain Res 366:96107
On the other hand, COX-1 selective inhibitor, ketorolac, and the non-selective COX-inhibitor, indomethacin -but not the COX-2 inhibitor- partially reversed the NPW-induced alleviation in gastric oxidative injury, indicating that the antioxidant properties of NPW involve a COX-1-dependent mechanism
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doi: 10.1016/S0140-6736(23)02750-2
Cardiovascular Safety Heart rate increases of approximately 2-6 beats per minute have been observed with orforglipron across clinical trials, consistent with the class effect of GLP-1 receptor agonists
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