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doi:10.1136/gutjnl-2020-323082

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"Yes definitely an increase [in moles], but not a ridiculous amount

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49.9 HU ( p = 0.001)]

Varus alignment, often associated with medial compartment OA, increases compressive forces on the medial meniscus and cartilage, accelerating cartilage breakdown and osteophyte formation (Valente et al., 2025