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10.12048/j.issn.1674-229X.2024.10.001 136 ZhangC.LiJ.WangL.MaJ.LiX.WuY.et al (2024)

However, this accumulation could reflect either metabolic dysregulation or simply reduced renal clearance [170, 171]

In our study, high glucose resulted in changes of mitochondrial morphology, which further increased ROS production and decreased MMP of RGCs

In the SURMOUNT-1 trial, participants without diabetes achieved weight reductions of 15% to 20.9% from baseline over 72 weeks, depending on dose, compared to 3.1% with placebo

When its used as an alternative: Mounjaro may be a suitable option if you have type 2 diabetes and are looking for more advanced weight management than what Ozempic provides

It can be provoked with high-histamine foods to see if levels increase