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Individuals under 18, pregnant or nursing individuals, or those with active medical conditions - per the brand's own label caution, physician consultation is recommended before use in these groups

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Low SAM, elevated SAH or a reduced SAM/SAH ratio can therefore represent different types of impaired methylation

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doi: 10.3389/fendo.2018.00233 29 WangLLiPTangZYanXFengB