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A general finding is that obese patients fulfilling criteria for MetS together with low IGF-1 plasma levels tend to develop a worse cardiovascular disease outcome than those with mid-normal to high-normal IGF-1 levels [213]

Tao, S., Wang, X., Wu, L., Shen, C

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Animal studies involving surgically severed tendons document measurable improvements in tensile strength and tissue integrity within 14 to 21 days of administration