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The variable R group gives rise to the four most commonly known cobalamins: cyanocobalamin (CNCbl), methylcobalamin (MeCbl), adenosylcobalamin (AdCbl, also known as cobamamide or 5-deoxyadenosylcobalamin), and hydroxocobalamin (OHCbl)

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The time taken to reach this threshold level in the control animals was 12 min

This once-weekly cadence is one of the practical advantages of the long half-life: a single anchored injection covers the entire week, and there is no daily-dosing burden to maintain