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Since all RSS coexist in biological systems and per- and polysulfides are rather unstable molecules, research on the role of particular forms of RSS is challenging

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Supplementing it orally, at standard doses, is unlikely to stress the liver

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The most common side effects are gastrointestinal: nausea (30-44%), diarrhea (19-30%), constipation (10-24%), and occasional vomiting (9-24%)