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Weight loss plateaus are a normal adaptation after 3 to 6 months of consistent progress

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Future Research Priorities in Safety and Tolerability Despite the promising role of GLP-1-based therapies, several areas require further investigation to ensure their long-term safety in adolescents: Long-Term Metabolic Effects: Future studies should evaluate how sustained GLP-1RA use affects insulin sensitivity, lipid metabolism, and cardiovascular health over decades

Statements Author contributions GC: Conceptualization, Data curation, Investigation, Methodology, Writing original draft, Writing review & editing

The article names severe upper abdominal pain radiating to the back as a sign of possible acute pancreatitis, along with persistent severe vomiting, vision changes, and signs of hypoglycemia in insulin-treated patients

The effect may be subtle