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Researchers note that the 12mg cohort had not reached a weight loss plateau at 48 weeks, suggesting efficacy may continue to increase with longer exposure

These trials will be decisive Phase 2 results are promising but involve smaller samples and shorter follow-up than what regulators require for approval decisions

How effective is Retatrutide for non-diabetic weight loss

Retatrutide (20 mg) is a synthetic peptide designed for metabolic and endocrine research

Tirzepatide is MHRA-authorised as Mounjaro for type 2 diabetes and as Zepbound for weight management

Mounjaro and Zepbound (tirzepatide) target an additional hormone called GIP, producing even greater average weight loss