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A study of topiramte pharmacokinetics and tolerability in children with epilepsy

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Carnitine analogs produced by the gut microbiota can colocalize with carnitine in the white matter of the brain and inhibit carnitine-mediated FAO in cell culture models of mouse CNS white matter, affecting the hosts nervous system, which provides a new perspective for understanding the complexity of the gutbrain axis [252]

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The continuous production of ONOO could suppress the activity of glutathione reductase by nitration modification, thus collectively reducing detoxification and blocking DNA damage repair

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