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Vegans and vegetarians have a significantly reduced capacity to synthesize TMAO from carnitine, which may explain the cardiovascular health benefits of these diets. The scientists also suggested that people might want to think twice before taking carnitine, calling for further research into the safety of the dietary supplement

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In vitro studies performed on mouse and human islets validate that DPP-IV inhibitors can mediate direct effects on islet hormones ( Figure 4 )

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