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These investigations have examined the compound's biochemical effects in cultured cells and animal models as part of broader research into NNMT and cellular metabolism Importantly, these findings relate to preclinical research and should not be interpreted as evidence of established clinical efficacy, safety or therapeutic benefit in humans

Discussion In this study, we showed that cryopreserved canine primary hepatocytes in a sandwich culture are an appropriate in vitro model for canine ITZ-associated hepatotoxicity

Although promising, most of the published studies have been in animal models rather than large-scale human clinical trials

April 23, 2014

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Besides weight reduction, Wegovy may offer additional health advantages