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doi: 10.1113/jphysiol.2006.125799

To determine whether the improved PK properties of the QMP-engineered fusions would translate into enhanced efficacy, we repeated the GTT in human FcRn Tg32 mice

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2012 displays favorable DMPK properties and in vivo efficacy To ensure suitability for in vivo testing, a series of in vitro DMPK assays were performed to assess plasma and metabolic stability of 2012

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