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These medications are supported by extensive randomized controlled trial data and are recommended by the American Diabetes Association (ADA) as preferred agents for many patients with type 2 diabetes, particularly those with established cardiovascular disease or chronic kidney disease

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the main pathways differing between the FI group and the GSH group were Gap junction, Aminoacyl-tRNA biosynthesis, Pyrimidine Metabolism, D-Amino acid metabolism

Cryopreserved samples from 3 additional healthy controls and 3 additional patients that could not be analyzed fresh were also included in the study after confirming that ROS and glutathione levels in cryopreserved samples fell within the value range of fresh control and patient samples

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