Second, this analysis focused exclusively on a subset of GLP-1 RA therapies (specifically semaglutide and tirzepatide) and did not account for other common PCOS treatments, such as metformin, combined oral contraceptives, or anti-androgen therapies
Tesamorelins risks (including a glucose signal) are characterized
We know that GLP-1s work across the body and the brain to result in weight loss and that they tamper spikes of feel-good chemicals like dopamine, she says
Based on observational data, a 2011 report highlighted an increased risk of pancreatitis and pancreatic cancer in patients using incretin therapy (Elashoff et al., 2011), prompting a warning from the Food and Drug Administration (FDA) regarding the pancreatic safety of GLP-1 RAs (Administration, 2013)
Taking more than prescribed within a 24-hour period can lead to severe side effects, most notably dangerously low blood sugar levels, particularly if youre also on insulin
The risk of developing type 2 diabetes, heart disease, and certain cancers decreases substantially