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Pinealectomy i.e., abolishment of the melatonin rhythm, leads to a more rapid circadian adaptation to phase shift in rats (80)

GSH preserves mTORC1 signaling activity and prevents the ISR during cystine deprivation and this protective function is supported by its role as a cysteine storage molecule

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Am J Physiol Endocrinol Metab (2013) 305(8):E94250.10.1152/ajpendo.00304.2013 259 ListEOBerrymanDEFunkKJaraAKelderBWangFet alLiver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles