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Patients often describe feeling more in control of food choices and less prone to overeating, which supports sustained progress

According to a recent detailed review published in the medical journal, Gastroenterology , sustained GLP-1receptor activation is associated with weight loss in both preclinical and clinical studies

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In its breakdown of metabolic functions, GIP-mediated glucose-dependent insulin release is credited with improved fasting and postprandial glucose, while potential GIP-driven increases in metabolic rate are described as possibly supporting a sustainable caloric deficit