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Some medications may cause stinging, burning, or aching during or after the injection

doi: 10.1126/sciadv.aax6208 168 SunMWuWChenLYangWHuangXMaCet al

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If soreness persists beyond 48 hours or is accompanied by redness, swelling, or warmth, contact your prescribing physician

The changes in 17-estradiol levels with aging are mirrored by the decline of collagen and elastin levels, which are shown in Fig

That's not always very obvious