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Researchers study this isolated segment to better understand whether specific functions can be linked to this particular region of the peptide

Diabetes 51 , S434442 (2002)

doi: 10.1016/j.freeradbiomed.2019.05.035 286 ValdsA.Ortega MorenoL.Rojo RelloS.OrduaA.BernardoD.CifuentesA

Reactions of reactive oxygen species (ROS) with curcumin analogues: structure-activity relationship

Moreover, APX-115 treatment effectively inhibited mitochondrial and peroxisomal dysfunction, suggesting pan-Nox inhibition as an effective therapy.Nuclear factor erythroid 2-related factor 2 (Nrf2) is another emerging treatment target to counteract oxidative stress and inflammation in CKD [65]

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