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Injection burden 1 weekly + 1-2 daily injections Best for Most users
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TGR5 activity appears to not have been lost in type 2 diabetic humans whereby the infusion of CCK, or rectal taurocholate, causes GLP-1 and insulin release via the TGR5 axis in colonic L-cells and pancreatic -cells respectively (341, 342)
doi:10.1016/j.yebeh.2020.107608
10.1016/j.bbrc.2019.06.112 46 ZhangY.CaoX.LiP.FanY.ZhangL.LiW.et al (2020)
When functioning normally, cortisol helps mobilise energy stores during periods of stress by promoting gluconeogenesis (glucose production) in the liver, increasing protein breakdown, and facilitating lipolysis
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