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SAM's many roles: SAM is the primary methyl donor, used in DNA/RNA methylation, protein modification, and synthesis of neurotransmitters and hormones

Primary carnitine deficiency PCD is a rare genetic disease caused by mutations in the SLC22A5 gene, which leads to dysfunction of the carnitine transporter OCTN2, thereby hindering the entry of carnitine from the blood into cells and the reabsorption of carnitine by the kidneys

We study the methionine cycle of the Reed-Nijhout model by developing a simple stylized model that captures its essential topology and whose kinetics are analytically tractable

This finding dramatically expands therapeutic options for androgen deficiency, which affects a significant proportion of the male population at an advanced age

Immunol Allergy Clin North Am

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