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Both represent significant advances beyond single-target GLP-1 agonists

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Cea Soriano L, Johansson S, Stefansson B, Rodriguez LA

Consistent with the role of KG in de novo carnitine synthesis through TMLHE, we observed an increase in H2AX foci following TMLHE knockdown, which was rescued by l-carnitine and acetylcarnitine, but was not markedly rescued by KG, propionylcarnitine or butyrylcarnitine (Fig

Key Takeaway: Liposomal delivery is designed to support absorption at the cellular level