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While GLP-1 has been Targeting Type 2 Diabetics While Type 1 diabetics are the ones that use DexComs CGM systems, which are compatible with insulin pumps, the company is targeting Type 2 diabetics with the launch of Stelo

Zhang S et al

Abbreviations GLP-1: Glucagon-like peptide 1 PCOS: Polycystic ovary syndrome RNA-seq: Ribonucleic acid sequencing functional MRI: Functional magnetic resonance imaging GLP-1 RAs: Glucagon-like peptide 1 receptor agonists NTS: Nucleus solitary tract DHEAS: Dehydroepiandrosterone sulphate PCOM: Polycystic ovarian BMI: Body mass index AE: Adverse event SAR: Serious adverse reaction SRL: Subject randomization list UN: Unique number DXA: Dual-energy X-ray absorptiometry VAT: Visceral adipose tissue TFEQ-R18: Three-Factor Eating Questionnaire-R18 RIA: Radioimmunoassay CV: Coefficient variation NGT: Normal glucose tolerance 2h-OGTT: 2-h oral glucose tolerance test IFG: Impaired fasting glucose CR: Cognitive restraint UE: Uncontrolled eating EE: Emotional eating MSG: Monosodium glutamate ITT: Intention-to-treat PP: Per-protocol DE: Differential expression FDR: False discovery rate CNS: Central nervous system References de Graaf C

Compared to L-arginine, an advantage to supplementation with L-citrulline is that intestinal catabolism of L-citrulline is limited since it is not metabolized by arginases, and the activity of arginosuccinate synthase is low in enterocytes [2]

While researchers primarily use GLP-1 antagonists for other medical purposes, they continue to explore their potential in metabolism and weight management

GLP-1 should not be used for people on other blood sugar lowering medications