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Kim K-B, Nam YA, Kim HS, Hayes AW, Lee B-M (2014) -Linolenic acid: nutraceutical, pharmacological and toxicological evaluation

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Apart from the advantageous effect, delivery of miRNA to the targeted site suffers from several drawbacks like high toxicity, failure to transport enough miRNAs to the target tissues, and lack of targeting and stability in cellular environment [110]