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Why Are GLP-1s Not Recommended During Pregnancy
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The pivotal trials behind that class include STEP (semaglutide, The New England Journal of Medicine , 2021), SURMOUNT (tirzepatide, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)
"When you think about normalizing obesity and the treatment of it, people are used to taking a pill for hypertension or for high cholesterol, so here's another way that it just normalizes it to take a pill for a condition that we know is a chronic disease," Narula said
Key Takeaways GLP-1 receptor agonists are mainly used for weight management and diabetes, but they also seem to affect the brain
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