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IMiD drugs bind an E3 ligase (CRBN) and cannot bind neosubstrates in its absence

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Fortunately, effective treatment options are available, including medication, surgery, implantable devices, lifestyle changes, and therapy

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These treatments include: The contraceptive pill , to regulate periods and reduce the long-term risk of endometrial cancer Fertility medicines , including letrozole and clomifene, which support ovulation when trying to conceive Anti-androgens , such as spironolactone, for excess hair growth Hair reduction treatments , such as prescription creams and laser treatments, for excess hair growth Your healthcare provider will personalise these treatments to your goals and health history

Bodies respond differently