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This product is not approved by the FDA for human consumption, medical use, or veterinary use

594 The OPTION-DM study determined which monotherapy and combination therapy of amitriptyline, duloxetine, and pregabalin are the most clinically efficacious

There was a death within one of the clinical trials that was related to cardiovascular dysfunction

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Confluence exploration: cysteine metabolism, ferroptosis, and AA pathogenesis Ferroptosis represents a distinct mode of cell death, instigated by lipid peroxidation and markedly reliant on iron ions (Jiang et al

2011;471(7339):S101