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A randomized controlled trial (RCT) demonstrated that after 6 months of supplementation with 1.2 g/d of EPA + DHA for patients with knee OA, the WOMAC pain score decreased by 23% ( p = 0.02), and the synovial inflammation assessed by MRI was relieved (42)

If a patient has underlying medical conditions, is pregnant or breastfeeding, has unrealistic expectations, or if I don't believe the potential benefits outweigh the uncertainties, I will recommend alternative treatment options instead." In many ways, yes

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No randomized trial has compared cagrilintide against tirzepatide directly

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