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In white adipose tissue of obese, insulin-resistant and aged mammals, NNMT is dramatically upregulated and because it consumes both the universal methyl donor (SAM) and the NAD precursor (nicotinamide), its hyperactivity simultaneously depletes the cellular methylation reserve and the NAD-salvage pool [1,2]
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Effects on Neurotransmitters Although the primary mechanism of DIHEXA focuses on BDNF pathways, activation of these pathways may secondarily affect the levels and function of certain neurotransmitters, such as acetylcholine, dopamine, and serotonin
Cognitive support: as noted in the JAMA data, executive function and verbal memory improvements have been documented, making it relevant for patients with early cognitive concerns
Contents: 240 tablets (81.6g total, 340mg per tablet)
US$ 28.02
US$ 21.70
US$ 24.79
US$ 28.49
US$ 23.22
