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1.36 million particles in the 300 class, 4.4 million in the 150 class, and 7.1 million in the 100 class were further subjected to 2D classifications

617 Exposure of astrocytes to -amyloid down-regulates expression of glutamine synthetase, 618 and in animal models, glutamine synthetase expression is reduced in astrocytes surrounding -amyloid plaques

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Thus, these TCM monomers represent promising candidates for future AR therapies

The in vivo fluorescence in our experiment is maximally downregulated under Al toxicity

While the pro-inflammatory effect of microcrystalline UA is well-established 3,20 , there are several indications that soluble UA free of UA crystals has protective effects against inflammatory mechanisms and toxicity 50 with effects on macrophage polarisation towards the anti-inflammatory M2 phenotype 51