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The graphic above summarizes six mechanisms researchers are currently studying

J Rehabil Med 52(4):jrm00048

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The IRA negotiated prices (38% to 60% below 2023 list prices for the first ten drugs) remain substantially above cost-plus manufacturing prices, but they establish a government-sanctioned maximum price that undercuts the list price premium that patent defense was designed to maintain

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Trends in Cardiovascular Medicine , 33(3), 159-166