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Once-Weekly Semaglutide in Adults with Overweight or Obesity (STEP-1)

This included heart attack and stroke, by 20% in adults with obesity or overweight who already had cardiovascular disease, even without diabetes (Reference)

When you lose muscle during weight loss, your resting metabolic rate decreases, making it harder to maintain your results long term

Why patients love it: You can see what youre doing, and the fat layer is typically even, which helps the medication absorb smoothly

Xie C, Alkhouri N, Elfeki MA

No acute effects of exogenous glucose-dependent insulinotropic polypeptide on energy intake, appetite, or energy expenditure when added to treatment with a long-acting glucagon-like peptide 1 receptor agonist in men with type 2 diabetes