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KEYWORDS: Direct oral anticoagulants, dabigatran, rivaroxaban, apixaban, edoxaban, stroke prevention, atrial fibrillation, deep vein thrombosis, pulmonary embolism, warfarin For the past 60 years, warfarin had been the only oral anticoagulant available for the prevention and management of thromboembolic events

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doi: 10.1074/jbc.272.19.12422 211 WongK