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(2018) reported that GLP-1 induces either an increase or a decrease of spontaneous firing rate in GLP-1R expressing BNST neurons

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Abbreviations ACh: Acetylcholine AChE: Acetylcholinesterase ChAT: Choline acetyltransferase DMN: Dorsal motor nucleus of the vagus IBD: Inflammatory bowel disease IL-1: 1interleukin-1 IL-21: Interleukin-21 JAK2-STAT3: Janus kinase 2- signal transducer and activator of transcription 3 LCMV: Lymphocytic choriomeningitis virus mAChRs: Muscarinic acetylcholine receptors nAChRs: Nicotinic acetylcholine receptors NE: Norepinephrine NF-B: Nuclear factor kappa-light-chain-enhancer of activated B cells NTS: Nucleus tractus solitarius PAMPs: Pathogen-associated molecular patterns TNF: Tumor necrosis factor VNS: Vagus nerve stimulation 2 -ARs: 2 -adrenergic receptors References Balkwill F, Mantovani A