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Recently, however, semaglutide, a GLP-1 receptor analog (GLP-1 RA), has been formulated in a way to allow for oral absorption [15]

The FDA has approved a handful of GLP-1 and dual GIP/GLP-1 medications for chronic weight management

In a recent study published by Nauck et al., all GLP-1 RAs have a common mechanism of action in terms of controlling blood glucose levels, i.e., increased production of insulin during hyperglycemic states, suppressing glucagon secretion, delayed gastric emptying, preventing postprandial glucose spikes, and lowering caloric intake and BMI [3]

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Of course, those goals can vary

Some primarily reduce stomach size, while others also change how nutrients are absorbed during digestion