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Proc Natl Acad Sci U S A 105:1356813573 Shibata T, Kokubu A, Saito S, Narisawa-Saito M, Sasaki H, Aoyagi K, Yoshimatsu Y, Tachimori Y, Kushima R, Kiyono T, Yamamoto M (2011) NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer
Pesticides increase the production of reactive oxygen species (ROS) by disrupting the oxidant/antioxidant equilibrium, which is linked to mitochondrial dysfunction 53
In these patients, parenteral (not by mouth) vitamin B12 is often used initially to ensure rapid absorption and resolution of the deficiency
Then 32-plane z-stacks were obtained every 25 min for up to 40 h
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