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Serious but rare adverse effects include: Acute pancreatitis (patients should be advised to seek immediate medical attention for severe, persistent abdominal pain) Gallbladder disease, including cholecystitis and cholelithiasis Acute kidney injury, particularly in the context of dehydration from gastrointestinal side effects Hypoglycaemia, especially when used alongside other glucose-lowering medications Thyroid C-cell tumours (observed in rodent studies

Recent clinical discussions on platforms like the HealthiHer Podcast highlight that the medication may help reduce systemic inflammation and potentially improve kidney function in specific patient populations

Defronzo, R

This can result in a more radiant complexion, potentially reducing the appearance of dark circles

Alternatively, if the vial has positive pressure, pushing water in becomes difficult because you are compressing the air inside

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