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Pterostilbene treatment of 15 and 30 M showed reduced histamine secretion and calcium uptake, overall indicating its ability to prevent degranulation, histamine release, and intracellular calcium level of mast cells [209]

There is also some limited evidence suggesting that individuals who carry certain polymorphisms in genes involved in vitamin C transport and detoxification mechanisms may have lower plasma vitamin C concentrations even with high vitamin C intakes (see also Vascular complications of diabetes mellitus) (reviewed in 27)