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(2018) 6:e1196252

P-CTX (procollagen type I C-terminal cross-linked telopeptide), a marker of bone resorption, increased significantly in the semaglutide group compared to placebo (p = 0.021)

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Furthermore, inflammation outside the brain can activate both immunological and somatic signals via both humoral and retrograde neuronal signals which largely involve the vagus nerve (24)

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