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"The catalytic mechanism of glutathione reductase as derived from x-ray diffraction analyses of reaction intermediates"

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Anti-inflammatory research: GHK-Cu suppresses pro-inflammatory cytokines including TNF-, IL-6, and TGF-, making it directly relevant to inflammation and skin barrier dysfunction studies

Concurrently, LPS significantly elevated TNF- and IL-6 levels in BALF, which were markedly decreased in mice pretreated with 10 g/g GHK-Cu

The effect is promising, but again, it came from a very small sample, so read it as "deserves more research" rather than "proven for everyone." Several small clinical trials on oral glutathione, some using doses similar to this product, have shown modest reductions in melanin index and improvements in skin brightness over 4 to 12 weeks