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This process, called central sensitization, involves neuroinflammation, specifically activation of microglial cells in the brain and spinal cord

This is called fragmentation

Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)

WHY B12

When bruising is severe, recurrent, or accompanied by other signs such as mucosal bleeding (nosebleeds, gum bleeding), petechiae (tiny pinpoint red spots), or systemic symptoms, underlying medical conditions should be considered

As always, consult your local expert toxicologists to help guide management decisions