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But those processes need the right environment to function optimally

71 In addition, extra-mitochondrial localization of branched-chain -keto acid dehydrogenase (BCKDH), a rate-limiting enzyme in BCAAs metabolism, has been reported in type 2 diabetic rat model (OLETF)

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This temporal progression indicates that 5-amino-1MQ may serve as more than a simple enzyme inhibitor, potentially acting as a metabolic reprogramming agent that fundamentally alters cellular energy management strategies over extended periods