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Given the natural fluctuations in hormone levels and the intricate rhythms of human physiology throughout the day and over a persons lifetime, there is concern about the uncertain health ramifications of sustained elevation of incretin activity over decades of treatment

Finally, think about cost and accessibility

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June 12, 2018

both these factors may improve brain health and explain the reduced risk of conditions like Alzheimers disease and dementia. While GLP-1RA drugs display effectiveness against a wide array of health problems, the magnitude of associated benefits is modest about a 10 percent to 20 percent reduction for most outcomes

therefore, it is too early to predict if GLP-1s will provide benefit for patients with these conditions