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It is important to mention that, although COX-2 has traditionally been seen as an enzyme that is expressed only under pathological conditions, it has detrimental effects on the pathophysiology of diseases such as Alzheimers disease [238]

The effect of omega-3 fatty acids on sarcopenia: mechanism of action and potential efficacy

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This covers direct neurotransmitter modulation (Selank, Semax, BPC-157, Pinealon), neuroinflammation reduction (Selank, BPC-157), BDNF enhancement (Semax), gut-brain axis repair (BPC-157), and circadian rhythm normalization (Pinealon)

doi: 10.1016/S0016-5085(12)60176-0